For continued response data.

As we learned that there are three assumption for employ ANOVA:

independent observations

normally distributed data for each group

equal variances for each group

But for REPEATED MEASURES data the first one will be violated so we us

some appoaches to accourt for the correction. but the rest two

assumptions should still be met or not?

for example,

person Before Drug_A Drug_B Drug_C

1 94 67 90 67

2 57 52 69 55

3 81 74 69 73

4 82 59 71 72

5 67 65 74 72

6 78 72 80 72

7 87 75 106 74

8 82 68 76 59

9 90 74 82 80

....

<this is a cross-over study design, the three drug are measured at the

same subject four times. the response variable is heart reate, the

DRUG B is placebo>

my code is;

PROC GLM DATA=mydata;

MODEL Before Drug_A Drug_B Drug_C =/NOUNI ;

REPEATED hrate 4 CONTRAST(1)/ PRINTE SUMMARY;

REPEATED hrate 4 CONTRAST(4)/ PRINTE SUMMARY;

RUN;QUIT;

then i got a output about the spericity test and something else. but

any other thing i forgot? are ther other assumption should be tested?

Any suggestion or reference are appreciated! thanks in advance.

Johson Chang